Showdowns with Sylar affect the fates of Peter, Nathan and Matt; a new sinister force begins stalking heroes; twins Maya and Alejandro search for help coping with their deadly abilities.
Upon his return to New York, Suresh finds a previously undiscovered painting that foretells the death of someone close to him; Claire and H.R.G. pursue their own agendas; Maya uses her deadly abilities to free Alejandro from a Mexican prison.
In Ireland, a lost hero discovers that a mysterious woman (Kristen Bell) is willing to kill to find him; Matt and an unexpected ally fly to Philadelphia to hunt down the "boogeyman"; Monica tries to come to terms with her new abilities.
Matt enlists unlikely help as the attacks on people with abilities continue; Claire's efforts to hide her healing power at her new high-school are in danger; as part of his new job, Suresh must track down the Haitian.
The team goes to Houston to investigate a series of seemingly random murders at construction sites; the team notices a distinct change in Reid's demeanor.