Skye (Maisie Williams), an impulsive teenager with a terminal illness, befriends Calvin (Asa Butterfield), a 19-year-old hypochondriac who is afraid of his own shadow. When Skye recruits Calvin to help her carry out her unconventional bucket list of things to do before she dies, he learns to confront and conquer his own fears, including his greatest fear of all: talking to the beautiful, but seemingly untouchable, Izzy (Nina Dobrev).