American astronauts Buzz (Gene Hackman), Jim (Richard Crenna) and Clayton (James Franciscus) are stranded in space on their return journey from a new space station when malfunctioning rocket boosters bring the craft to a halt. With the men drifting in orbit, facing death from declining oxygen levels in the shuttle, NASA director Charles Keith (Gregory Peck) quickly mobilizes to launch a bold rescue mission -- but a hurricane headed for the launch site may ensure the astronauts' demise.