시즌 1, 에피소드 1: Sink your teeth into meaty drama and intrigue with House, FOX's new take on mystery, where the villain is a medical malady and the hero is an irreverent, controversial doctor who trusts no one, least of all his patients. On the compelling series premiere episode, Dr. Gregory House, a brilliant diagnostician but devoid of bedside manner, and his elite team of young medical experts rush to save the life of a kindergarten teacher (guest star Robin Tunney) who started speaking gibberish and passed out in front of her class. What looks like a possible brain tumor does not respond to treatment and provides many more questions than answers for House and his team as they engage in a risky trial-and-error approach to her case. When the young teacher refuses any additional variations of treatment and her life starts slipping away, House must act against his code of conduct and make a personal visit to his patient to convince her to trust him one last time.