The year is 4044. The battle between the blood-thirsty Illuminati forces and the human resistance, known as the Allies, rages on. As Dr Jeckyl works to reverse the RX2 sociopathy gene found in Illuminati DNA, Allies leader Princess Kali DiVine sends space rough neck Van Helsing and his rowdy associate Big Foot on a mission to escort Tickles The Clown back to headquarters.