Brock Cuchna

Depressed over the failure of his marriage, Luke resorts to a self-help tape and suddenly realizes that he already knows who his soul mate is. Later, when his sister Liz (recurring guest star KATHLEEN WILHOITE) returns to town and announces that she and T.J. (MICHAEL DeLUISE) are getting married, Luke finds Jess (former series star MILO VENTIMIGLIA) and convinces him to attend the wedding. Meanwhile, Lorelai is completely stressed as opening day at The Dragonfly Inn approaches, and Rory pretends not to be interested when Lorelai tells her she overheard Dean (former series star JARED PADALECKI) and his wife, Lindsay (recurring guest star ARIELLE KEBBEL), fighting.

Izzie spends time with a fellow cancer patient and contemplates whether or not to undergo a risky surgery, as Mark wants to take his relationship with Lexie to the next level.

The Walkers try to help Kevin and Scotty reunite; Jack starts to pursue new ventures; Luc and Sarah share exciting news.

Andy and Pam try to save an 18-year-old college student in need of a double lung transplant but run into a road block that might not allow her to be eligible for a new set of lungs.