Diego Aguirre

When the leader of a drug cartel and one of the world's most wanted men, Antonio Vargas (guest star David Zayas), is apprehended by the team, the entire FBI headquarters is put at risk when his henchmen unveil a terroristic threat to free him. During the turmoil, Isobel must make the difficult decision whether to sacrifice her conscience or her career, on FBI.

Holmes and Watson try to work a stateside investigation from London when someone close to them is gravely wounded by an unknown perpetrator in the United States. However, Holmes' stateside legal trouble - the result of a confession to a murder he didn't commit - threatens to derail their efforts.

Sharpe (Freema Agyeman) struggles when a case hits too close to home and Iggy (Tyler Labine) uncovers a patient's surprising past. Meanwhile, Floyd (Jocko Sims) makes progress in his personal life after some difficult news.

When Elizabeth discovers that the White House attackers had support from overseas, she tries to hunt down those responsible without starting a war. Also, Henry comes face to face with one of the attackers.

Captains John Abraham and Maya Dobbins head to a war zone when they are assigned to opposite sides of the courtroom in the case of Marine charged with abandoning his post during combat, resulting in the deaths of three soldiers. Also, Major Trey Ferry must iron out a diplomatic spat, and Lt. Harper Li works to balance her duties to the Corps with planning her wedding.