When a serial killer in Buffalo sends a videotape of one of his crimes to the BAU, the team discovers a message from the murderer that begs for help in stopping the killing.
When a woman's burned body is found in a car with signs that her child was kidnapped, Brennan and Booth suspect the father, Carl Decker. But things get complicated when Decker turns out to be in the witness protection program. In two days he is scheduled to testify before a grand jury that his company has been sending defective body armor to Iraq.
House treats a patient whose chronic pain pushes him to the edge.
When a suspect voluntarily admits to killing a reality show celebrity chef in his own restaurant, Danny and Maria are convinced the suspect is taking the fall for someone. Also, Frank faces a moral dilemma when a longtime friend, Sen. Ted McCreary, asks for Frank's help to make a DUI go away, and investigative journalist Anne Farrell returns. Peter Coyote guest stars.
Tom feels a new Scavo's Pizzeria employee's interest in Lynette threatens him; Susan considers moving from Wisteria Lane; a neighbor's darkest secret.