Turk forgets to pick up Carla's brother (Freddy Rodriguez) from the airport the night before the wedding.
Turk takes an extra shift at the hospital hoping to get more time off for his honeymoon, but a patient's complications keep him there longer than intended.
When a young woman commits suicide, Danny is emotional since he promised to help her when her parents were taken from her. Meanwhile, the Reagans suffer a loss due to the project gangs. Joanna Gleason guest stars as Grace Newhouse and Kamar de los Reyes guest stars as Santana.
When Matty's goddaughter and her boyfriend are killed in a San Francisco park, Mac and the team investigate the crime and start to suspect that the 1970s Zodiac Killer has returned.
A case forces Ed Green to reveal his troubled past and puts his badge in danger.
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