Kate Anthony

With acting boss Jackie Aprile dying of cancer, Tony prepares for a power struggle with Uncle Junior. Christopher and his associate Brendan make trouble for themselves when they jack a truck full of DVD players. Tony's mother Livia finally agrees to live in a retirement community. Big Pussy and Paulie Walnuts are sent to find a stolen car.

Meredith and Cristina lie to each other about their relationships; George must discharge an elderly patient who is no longer sick but refuses to leave the hospital.

The nurses at Seattle Grace Hospital go on strike, leaving the doctors to fend for themselves; an elderly patient's friends (June Lockhart, Betty Garrett and Rae Allen) bring Meredith's mistake to light.

When a series of deaths occurs at Seattle Grace, the uncanny events bring out the doctors' superstitious sides and make Izzie nervous about Denny's surgery.

Bailey treats a young mother battling breast cancer; Derek learns more about Mark and Addison's relationship; the interns defend a resident's competence at a staff meeting.

A traumatic car accident fills the ER; Cristina has a crisis of conscience about her deceptive teamwork with Burke; Izzie pushes the boundaries of probation.