When the COVID-19 pandemic hits Seattle, the Station 19 crew lean on each other for support; Andy tries to make sense of her mother's return; a group of teenagers unintentionally starts a wild fire.
Andy becomes suspicious of the circumstances surrounding her mother's death; the crew works to evacuate a doctor from Pac-North hospital and find themselves in a life-threatening situation; Sullivan undergoes surgery for his chronic leg pain.
Hathaway and Ross ride in a health mobile dispensing free medical care in poor neighborhoods. Greene and Lewis enjoy the ER Halloween party together.
Gant feels intense pressure from Benton who Gant feels is too tough on him. Carter ignores Gant because he's tired of listening to his constant complaints.
Lewis confronts her fear of flying to travel in a rescue helicopter with Greene and assist a family of accident victims. Jeanie and Doyle keep a dead man on ice for cryogenic storage.