The hospital has a pipe break which causes a huge flood; Meredith quits therapy but Dr. Wyatt doesn't believe she is finished.
The Seattle Grace staff continue to mourn George's death; Derek receives a proposition from the hospital board.
Sydney Bristow is a grad student by day, international spy by night. Her happiness over new engagment is shortlived as she learns some horrible truths about who she works for.
The doctors form two teams to operate on conjoined twins; Bailey uses Meredith as a buffer between her and Ben; Alex learns a tough lesson; Teddy asks Cristina about Henry's surgery.
Jane gets the CBI involved in a case in Napa in order to focus on Sheriff McAllister, while Van Pelt and Rigsby finally take a trip down the aisle and get married.