Regi Davis

With Gideon missing, and Hotch and Prentiss off the team, the BAU investigates one of its most difficult cases yet as the remaining agents track a serial killer in Milwaukee who abducts women in public places by using his son as bait.

Frasier's vacation plans with Claire turn disastrous when Daphne, Niles and Martin show up at the same resort and Frasier starts dreaming about Lana.

On Brennan and Booth’s first official day back at their respective positions at the Jeffersonian and the FBI, things get exciting when remains are found at a fish farm under suspicious conditions, prompting them to investigate. After it’s discovered that someone harvested several of the victim’s internal organs before he was dumped in the water, Angela tracks down the seller and buyer of the organs to try to uncover important details in the case. Meanwhile, Booth readjusts to his position back at the FBI and discovers Aubrey has taken over his old office; Hodgins pushes Angela to showcase her photography work; and Cam struggles with her decision to choose work over her relationship with Arastoo.

As she endures aggressive treatment for her cancer, Izzie throws herself into planning Derek and Meredith's wedding.

Beckett is asked to assist with a narcotics investigation; when a routine undercover operation goes awry, Beckett is faced with dangerous men from the New York underworld.

After discovering the presence of a damaged alien vessel, Archer dispatches Tucker to its aid, but the engineer's encounter with a Xyrillian female has an unexpected side effect.