Will Truman (Eric McCormack), a handsome, successful Manhattan lawyer, and Grace Adler (Debra Messing), a beautiful, self-employed interior designer, are best friends. In fact, they're absolutely perfect for each other - except that Will just happens to be gay. When Grace receives an unexpected marriage proposal from her boyfriend, Will tries to be supportive of her decision but finally tells her that she's making a mistake, even though he's putting their friendship at risk. The situation is complicated by interference from Grace's socialite assistant, Karen Walker (Megan Mullally), and Will's outrageous friend, Jack McFarland (Sean Hayes).
Grace (Debra Messing) blames her relationship with Will (Eric McCormack) as the reason for her lack of interest in dating and decides they can no longer have fun together. Meanwhile, Jack (Sean Hayes) enlists Will's help when the IRS catches up with him. Julian McMahon ('Profiler') makes a cameo appearance as a handsome stranger in Grace's elevator. Megan Mullally also stars.
When the family takes a vacation to a casino, Hal gets banned from gambling and takes Malcolm and Reese on an ill-fated trek into the desert; Lois and Dewey win a free day of spa pampering; and Francis spends a lonely weekend at home with Craig.
Horatio and Speedle investigate the slaying of a hooker who is found dead under a bed in a plush beachside cottage, her naked body having been stabbed 23 times.
Finch challenges Maya to play a good practical joke.
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