In Ohio, Truck Hunters Shawn and Vince must track down and deliver a big rig filled with highly classified cargo but mid-route they pick up a mysterious tail. In Texas, a trailer filled with prized cattle is stranded on a track, and Marshall and Korchenko is the trucker's last hope to avert a disastrous collision. In New Jersey, brothers-in-law John and Gene are on the hunt for a hijacked truck full of a million dollars worth of laptops. And in Denver, Animal and Steve discover the perils of trying to deliver a hot load on a tight deadline, as the President's visit locks down the city's traffic grid.

The Jersey Boys, John and Gene, go to blows with a delinquent driver who isn't paying the bills on his truck lease. Ex Cons, Shawn and Vince, are sent to rescue a disabled tractor and its load, but this big rig is for the birds, literally. The Texans, Marshall and Korchenko, put their perfect recovery record to the test as a disoriented driver can't give them his whereabouts. And The Desert Dogs, Eric and Rob, a father and son truck hunting duo, must deal with a disgruntled driver who won't hand over his rig.

The Vets chase after a rogue driver who is out to stick it to the trucking company. The Jersey Boys are called in to rescue a driver who has been attacked by hijackers. The Texans are on a long hunt for 16 tons of frozen shrimp. And the Ex-Cons must track down a big rig that's been taken off the grid by a driver who thinks his truck is being followed by space aliens.

The Texans must hunt down and take back a stolen rig, before the thieves cross into Mexico. In Arizona, The Desert Dogs are called in to sniff out a snake. In Ohio, The Ex Cons kick into high gear hunting for a missing race. And The Jersey Boys are called in to take possession of a backhoe that a disgruntled trucker is holding hostage.

The Jersey boys, John and Gene, are called out of Newark and out of their element in search of a stolen tractor. The Ex-cons, Shawn and Vince, run into a series of unfortunate events after securing a truck with a high value load that needs to get to Houston. And the Vets, Animal and Steve turn up a load of produce that's not fit for human consumption.

The Ex-Cons chase down a missing load with a $5,000.00 bounty, but they're not the only bounty-hunters on the job. The Texans, Korchenko and Marshall, search scrapyards in the pre-dawn hours after a load of drilling pipe vanishes. And Jersey Boys, John and Gene, search high and low (and through strip clubs) in Newark's underbelly.