A poacher traps an endangered Iriomote cat on a remote island and boards a ferry. On board is Black Jack and Pinoko, along with a haughty politician. The wild cat escapes, causing a ruckus, and injuring the politician and a passenger's baby. The politician tries to get treated first by offering money, but Black Jack begins by operating on the Iriomote cat.

Pinoko and Sharaku are playing in a park when a stray dog grabs Pinoko's purse and runs off. They chase after the stray, but the dog is suddenly hit by a car outside of the park. Pinoko gets Black Jack to operate on the dog, and is successful.

Doctors at Manaka Hospital hold a conference to decide the successor to the recently deceased hospital director. There are two veteran doctors with 20 years experience, however, one other doctor with similar experience is overlooked, Dr. Shiitake.