A man is murdered — brutally stabbed with a steak knife. When Sgt. Ivan Mendez is called in to collect evidence it seems there is no hope of finding the killer's fingerprints. Without a print, even if a suspect is found there might not be a conviction.

An equipment salesman is murdered in his own driveway. His neighbor confesses that he and a relative murdered him and dumped his body. A K-9 unit has to sniff out the evidence.

A 16 year-old disappears from her father's house. A family friend brags about burying a girl "in the middle of nowhere." Canine handlers must take over where all others have failed.

A woman is ambushed in front of her home and shot at close range. Ballistics expert Kurt Tempinski must connect the dots, matching bullets to gun and gun to suspect.

When an 82-year-old woman is murdered in her home, all forensic serologist Gordon Calvert has is a small bit of blood and hairs as evidence. After a year of literally splitting hairs, he isolates one.

At a house in Poughkeepsie, a serial killer stores eight dead bodies. After nearly a decade, the dead bodies are unearthed in an attempt to bring the killer to justice.