Jesse Struthers goes on the run from the murderers of his father. He tracks down his younger brother Jake Struthers and together they vow to seek vengeance. After losing a bloody battle, he assimilates into an Apache tribe and married the chief's daughter. However, he is still haunted by the memory of his father's murder so he goes back to the world he left behind to bring about justice.

The murderers are now the owner of the Struthers family mine, and prominent figures in the town of Jackson Ridge, with Jake Struthers in his pocket. He partners with Mayor Deets. Just as a mysterious new player, Benjamin Brown, comes into town. Jesse learns of Jake's betrayal, and tries to blow up the mine. But his plan fails and instead he gets captured by Cole's men.

Jake and Jesse try to escape with murderer Cole's posse hot on their heels. In retaliation, Cole places a huge reward on their heads. Jake goes to enlist the help of local high-end call girl Sissy McHale as the Struthers boys hatch a plan. Meanwhile, Benjamin, following Sissy, offers to help. Their plan works,: Deets believes that Cole has betrayed him and Deets turns against Cole.

Jesse and Jake are shot by Cole's hire Vance. As Vance hunts down Jesse, Jake is injured and fights for his life with Sissy by his side. Meanwhile, Mayor Deets calls in the US Marshalls for the capture and arrest of Cole Roberts and his gang. In order to bait Jesse, his wife is abducted by Apache traitor Cuqusa and sold to Cole while former ally Benjamin makes an unexpected decision.

Jesse heads to Cole's camp alone to rescue his wife Ila against Jake's advice. Jesse demands his life be traded for Ila's. Jake, Deets, and the Marshalls sneak up on Cole's camp, but the real war begins when the Apache tribe shows up lead by Benjamin. Against the spectacular backdrop of the battle between the Indians, lawmen and outlaws, Jesse and Cole have a showdown of their own.