A look into the lives of two women whose houses are cluttered by things.

Extreme hoarders Chris and Laurie are spiraling out of control. Their possessions are destroying their relationships and transforming their homes into virtual prisons. Change won't be easy, but it's their only hope of reclaiming their lives.

A 55-year-old man plans to abandon his hoard only to move back with his mother, a fellow hoarder. A woman's hoard is so severe that she runs the risk of having her house condemned.

Extreme hoarder Mary Thompson is in denial while Anne Thomas fears she's passing down her compulsion to son Brendan. For decades they've had trouble discarding their belongings but will they finally gain clarity and get the help they so desperately need?

Wanda and Ray are extreme hoarders destined to lose their homes and live in isolation if they don't stop surrounding themselves with stuff. Making the change will be emotional and filled with anguish but they know that time is running out.

Two women who struggle with compulsive hoarding must get a handle on the piles of possessions that plague them. They have no choice but to ask for help - or they risk losing everything that matters to them and their families.