The "Lockup" franchise has become a staple of the MSNBC schedule, with each series in the franchise taking place in a different prison. This entry is filmed at the Wabash Valley Correctional Facility in the rural Indiana town of Carlisle. The prison's population, 2,200 male inmates, dwarfs the town's population of just several hundred residents. The majority of Wabash's inmates used to come from urban areas, but now they come mainly from rural farming communities, because of the rise of methamphetamine use. Many of the stories in the series revolve around the meth epidemic and the strict sentences that are handed down, including half brothers who are serving 54- and 35-year sentences for various meth-related crimes. Also housed at Wabash are several of Indiana's high-profile murderers.