Karl Pilkington investigates marriage, gaining insight into arranged nuptials and wedding planning in India and a scientific approach in LA, all before searching for an alternative path in Las Vegas.

Karl Pilkington investigates happiness, joining ultra-marathon runners and a group who finds pleasure in pain, then hanging out with some hip-hop clowns and a plastic-surgery addict, before trying a simple path to contentment.

Investigating why people have children, Karl goes to a fertility festival in Japan, a natural birthing center in Bali (where he even helps with a delivery), and meets an LA couple who are getting ready for the next step.

Karl Pilkington tackles questions related to vocation and money. In Japan, he visits a handyman and a brain training inventor. Then, he hangs out with a millionaire in South Africa before jetting to LA for a fashion show.

Karl looks at death. He shops for a coffin and attends a funeral with a parade in Ghana; meets some Filipinos who live and work with the dead; learns to cry and mourn in Taiwan; and returns to Britain where he makes a memorial.