A sunny weekend comes to a disturbing end when two young women vanish from a tourist area. Rookie detectives Bob and Roger are tasked with the investigation. When links soon emerge between a series of disappearances, fear takes a grip on the community.

A chance arrest leads Bob, Roger, and Kathy to an encounter with their prime suspect. It looks like they have caught the nation's roving killer. But can they prove his guilt, and can they hold on to him?

With a serial killer at large, the detectives race against time to capture him. As news of a bloody massacre hits the headlines, it becomes clear that he is on the move in another state. A final showdown pits Bob against his nemesis in a battle of wits.

In the summer of 1979, Detective Mike Brady is confronted by a grisly body count out in the desert of Nevada and Utah. Two years later, a Texan dental hygienist is held captive by a mysterious couple, and she soon learns about the man's violent past.

Pamela is kidnapped and taken from motel to motel across the Southwest by a faceless male assailant and his accomplice Sara. As their drug fueled violence spins out of control, even Sara begins to question her involvement with the charismatic killer.

The elusive killer slips free from the police. A manhunt is launched to find the man before he can kill again. In one last encounter, The Chameleon drives across the Texas countryside with a new captive held at gunpoint.