SEXIFY begins by introducing Natalia, a college student and scientist who would rather spend the weekend developing an app for better sleep than partying with her rowdy dorm mates. But when a professor tells Natalia her sleep app isn't exciting enough to win an upcoming tech competition, she pivots to something flashier: an app that improves women's orgasms. Her unlikely partners are Paulina, who is newly engaged to be married despite being in an unsatisfying relationship, and Monika, who is living in the dorms after getting kicked out of her rich father's home. To win the competition, the three women race to learn as much about sex as they can.