When two-year-old Hope Wilkins is abducted from her home, detectives Martha, Jack, and Charlie race to find her. The toddler’s father, his estranged wife, and their son all come under suspicion, but then a convicted child killer is connected to the case.

Charlie and Jack investigate an assault on nightclub owner Kirk Hawthorne and find Kirk’s sister, Ziggy, unconscious in the cellar. The hospital reports that Ziggy suffered a brain hemorrhage and a drug overdose. When a 19-year-old student dies from an overdose of the same drug, Charlie and Jack call Martha in on the case.

Martha and the team investigate a rape while also looking into two similar attacks that occurred in the area. Jack questions a serial rapist recently released from prison, and Charlie investigates the most recent victim’s husband: the station’s chief superintendent.

Terence Holland, the terminally ill founder of Euthanasia Action UK, is discovered unconscious in his home. With deadly levels of morphine and sleeping pills in his bloodstream, Terence may have tried assisted suicide—or someone with a more sinister motive may have attempted murder.

A young girl is stabbed but manages to flag down a taxi to the hospital. The detectives bring in the cab driver for questioning, suspicious that he didn’t call the police. Martha and Charlie later uncover nude pictures of the girl on her computer. Is her stepfather somehow involved, or were the pictures for someone else?

Martha’s neighbor Jonathan Moxton is found in his home bound and gagged, with serious head injuries. The prime suspect appears to be the man who found him, Saul Hammond, a paranoid schizophrenic. But as the team uncovers more about Jonathan’s complicated life, the case becomes personal for Jack, clouding his judgment.