Dean and Jerry perform a variety of comedy sketches concerning disruptive party guests, a man and woman reconciling after an argument, and a failing movie theater owner forcing a kid to purchase a ticket. Featured guests include blonde bombshell Marilyn Maxwell, comic dancers Barr and Estes, J.C. McCord, Jean Carson, and William McCutcheon-along with musical performances by Dean Martin.

Dean Martin and Jerry Lewis invite the mayors of their hometowns to appear on the show-Ralph Villani, Mayor of Newark, New Jersey and Walter Sterling, Mayor of Steubenville, Ohio. Other featured guests include singer Kitty Kallen and musical group The Skylarks.

Bob Hope serve as the Colgate show's host.

Bud Abbott and Lou Costello host with guests singer Evelyn Knight, dancer Hal Le Roy, specialty act Paul Remos and his Toy Boys.

Dean Martin and Jerry Lewis host, with featured guests choreographer Bob Fosse and actress Polly Bergen. Other performances include Frank Gallop and dancer Mary Ann Niles. Martin and Lewis performs a comedy sketch about an outrageous encounter between a couple at the drive-in and a theater attendant. Another sketch involves a pesky hotel guest who plays his trumpet.