Psychic medium Theresa Caputo is back and going global with her incredible gift of communicating with the dead. She still lives in Long Island, but her world looks a lot different now. She's single, a grandma and would be an empty nester if her daughter Victoria and her family weren't too comfortable to leave. With a tour coming up, Theresa decides to do a reading in town before heading off and ends up getting a surprise from her clients that she'll never forget.

An emotional Theresa finds out her father-in-law has passed and then feels his presence in the following days while shopping for Holy Water. Meanwhile, in a raucous group reading on Long Island, a son's path is endorsed by his late mother, a woman is reunited with her husband whose photo she keeps in her bra, and one woman becomes a believer when Theresa hits every message with a resounding validation.

Say ciao with Theresa and the Caputos as the big day finally arrives! Theresa and her family travel to Lake Como, Italy for the long-awaited wedding between Larry Jr and Leah. Spirit can't help but be part of the prep, as Theresa channels while shopping for her granddaughter's outfit for the wedding. While getting fitted for her own dress, Theresa spots a sewing machine identical to her grandmother's, which spurns a touching reading for the tailor. In a group reading, a woman who feels she never gets signs from her mother seeks Theresa's help.

Theresa is a nervous wreck trying to figure out what to pack for her very first visit to the UK. Before departing she sages Victoria's house and brings a pre-housewarming gift to encourage her to move out while she's gone. After her first tour performances there, she pulls off a jaw-dropping surprise on a double decker bus! A couple is blown away by the specific details that Theresa channels about their son. While at a cake shop, Theresa can't shake the feeling of a mysterious presence.