Improv meets the talk show platform in TRUST US WITH YOUR LIFE, a unique comedy format that puts celebrity guests' musings on their life experiences in the hands of able improv artists like Wayne Brady, Colin Mochrie, Brad Sherwood, and Jonathan Mangum. Host Fred Willard chats with the guests -- including the likes of Serena Williams, Florence Henderson, and Mark Cuban -- as they reminisce about memorable moments in their pasts before those recollections are brought to life through off-the-wall improv games and songs.