Some desperate schemes turn upon the use of unwitting clone Crystal, a manicurist tired of being manipulated, and Cosima's lab assistant, Scott.
Cosima takes a turn for the worst, forcing Sarah to take desperate action - with tragic consequences for those she loves. The Proletheans set their ultimate plan into motion. Alison and Donnie tangle with the law.
Art's intervention to get answers ruins Sarah's chance to bring Helena back to sanity, and the Orphans must choose whether to form an alliance with their creators.
A new player in the clone conspiracy turns up at Felix's door, sending him into crisis mode. With Cosima running out of options, Sarah struggles with the decision to surrender a crucial piece of leverage and make a deal with Dyad.
Sarah tries to bluff a ruthless enforcer that all is well at the Dyad Institute, while Alison's family finances pose problems. Helena is prisoner of the Castor clones, one of whom poses an immediate threat to those Sarah holds dear.