Brought up with a certain level of privilege, young Jacqueline Bouvier continually marries influential men of wealth and power.

Miscarriage and philandering mark the early years of the Kennedy family; John has dalliances with Marilyn Monroe while Jackie holidays with the Onassis family.

After the assassination, Jackie moves to New York and weds Aristotle Onassis; problems with Christina and, eventually, Ari cause the union to deteriorate.