Before morning's end, the team have to deal with seven cardiac arrest cases. Meanwhile, one crew navigates through busy roads in hopes of saving a father of two, and another is faced with a difficult decision.

Follows the staff located in the nerve centre that is the control room during the night shift, as they sift through the thousands of calls received including hoax calls and runaway patients.

The London Ambulance Services prepares for a demanding weekend, as locals leave work and head out to enjoy themselves. The team gather their resources, and brace themselves for an onslaught of unique challenges.

Katie and Sarah respond to a call on a Saturday evening to help a man who has collapsed, while the woman and daughter who made the call are given instructions on how to perform CPR.

The crew comes to the aid of a stabbing victim, a drunk driver responsible for rolling his car, and an alcoholic who refuses to accept their help.

Mike and Dave respond to a call about a woman's stomach pains, and discover that she is actually suffering from a heart attack. Meanwhile, a dispatcher receives a call from a woman in labour at the side of the road.