Addison heads to Los Angeles for a new job, though her new co-workers are not expecting her; her first case at the wellness centre could make or break her reputation with the staff.
Cooper hires someone to help Sam jump-start his new life as a single person; the doctors work with St. Ambrose Hospital's chief of staff to determine the cause of a baby's illness.
Addison needs Pete's assistance in treating a newlywed couple with difficulty consummating the nuptials; Violet urges a patient to leave his wife; Cooper tries to figure out why four sisters have a mysterious illness.
Addison invites her co-workers to a gathering, but no one responds; the wife of Violet's former boyfriend visits the clinic for treatment; Cooper counsels a lovesick young patient; Sam appears on a morning show to promote his book.
Addison cannot stop thinking of Pete; Violet's ex visits the clinic and Cooper is not happy to see him; Naomi and Sam's daughter secretly seeks Addison's medical advice.
Pete treats Charlotte's insomnia, Naomi goes on her first date since college and a patient asks Addison to conceal her fertility from her husband. When trying to help a patient caught between Sam and Cooper, Dell's secret is revealed.
Kate Walsh
Dr. Addison Montgomery
Benjamin Bratt
Dr. Jake Reilly
Kadee Strickland
Dr. Charlotte King
Paul Adelstein
Dr. Cooper Freedman
Brian Benben
Dr. Sheldon Wallace