Piers interviews Mark Riebe, an alleged serial killer who confessed to committing 13 murders along the Florida stretch of the Gulf Coast of the US before withdrawing the confessions and accruing only one conviction.

Morgan sits down with one of Missouri's most notorious serial killer, Lorenzo Gilyard, a seemingly ordinary man who murdered 13 times.

Once a successful businessman from The Bronx, New York City, convicted murderer Alex Henriquez has protested his innocence for nearly 30 years. He claims that the police framed him for the murders of two girls and one young woman.

For the first time, Piers Morgan comes face-to-face with a killer who wants to admit his crimes. In late 1973, 20-year-old Bernard Giles picked up five innocent young women hitchhiking.