Sam and Dean are stumped when they investigate a possible zombie case where an amnesiac man (guest star JOHN REARDON) dies and then revives himself once a day. After the guy is attacked by the goddess Artemis (guest star ANNA VAN HOOFT), Sam and Dean realize he's not a zombie but instead a titan – more specifically, Prometheus.
Olivia consumes a concoction Dr. Bishop gives her in hopes of stimulating her memory; the team investigates a series of robberies connected to shape-shifting.
A kidnapping rapidly escalates into a hostage situation, and authorities closing in discover that an unknown force has mind-blowing consequences; Fringe Division identifies a link between the incident and Massive Dynamic.
Jack discovers the alarming depth and scope of the organization to which he’s lost Amy. Meanwhile, Marcus and Madison engage in a fatal struggle; and Richard is forced to go on the run, but he recruits an unexpected partner along the way.
Tarkoff, an old friend of the family’s, pays a visit to Joanna and Freddie. Wendy, Freya, Ingrid and Dash attend an art gala where Wendy encounters someone from her past. Killian has doubts about his feelings for Eva.