As Shaun and Claire improvise to preserve a liver for a transplant, Andrews is pressured to partner with Melendez on a wealthy patient’s routine surgery.
Clark must save his friend (guest star Ryan Kelley) from a doctor who wants to control the boy's telepathic abilities. Sarah-Jane Redmond also guest stars.
The agents (David Duchovny, Gillian Anderson) may have uncovered the Cigarette-Smoking Man's (William B. Davis) true identity.
The agents investigate a group of anti-government terrorists who are experimenting with biological warfare; Scully notices a change in Mulder's behavior.
In an attempt to protect the rest of the team, Oliver registers for the Vigilante Registration Act; Lois becomes frustrated when Clark continues to brush aside her offers to help the team.