Hearts. Dr. Choi is tested when an erratic patient takes drastic measures, Dr. Manning questions the circumstances behind a young boy's broken wrist.
In the series premiere, veteran ER nurse Jackie Peyton bends the rules to create something good from a patient's senseless death, while concealing her addiction to a pain killer she gets from her secret boyfriend, hospital pharmacist Eddie.
When Danny and Baez investigate the kidnapping of a young girl, it brings back difficult memories for Danny. Meanwhile, Frank butts heads with Inspector General Kelly Peterson.
Holmes and Watson investigate after a BASE jumper is shot out of the sky and has his parachute sabotaged by two separate people; Joan's sister thinks she sees Shinwell with a member of his old gang.
The team finds itself investigating the murders of three different people, only to discover that two of the murder victims are linked and may have been killed by the same person. One of these cases becomes personal for Mac.