Allison, a successful, driven doctor, runs into Amy, a larger than life, eccentric woman who claims to be her "guardian angel," and whose mission is to help Allison loosen up and see her life from a new perspective.

When Amy encourages Allison to face her fears, Allison asks Joey McIntyre to help her repair a relationship with an old friend.

Amy tries to get Allison to cut loose by taking her to a nightclub; Marv runs a background check on Amy.

Marv objects when Allison wants to make changes at the dermatology practice; Amy creates a temporary position for herself at the office to help Marv and Allison work things out.

Amy puts a plan into motion that backfires when Allison meets her soul mate before she is supposed to.

When Amy loses her powers after she cheats at a game, she must perform 10 good deeds to earn them back.