Released from prison after three years, "Ace" Bernstein plots revenge against the colleagues who betrayed him. With his trusted aide/chauffeur Gus Demitriou acting as a front for his race horse investment, Ace seeks to reverse the sagging fortunes of a famous racetrack. Meanwhile, four dissolute gamblers at the race track - Jerry, Marcus, Renzo and Lonnie - pool their meager resources to make a Pick Six bet that could be worth millions. A key to their fortunes is a long-shot horse trained by Turo Escalante, a self-made success story with loads of talent and few scruples, whoʼs also training Gus/Ace's colt. Walter Smith, another more grizzled trainer, sees classic potential in an untested thoroughbred with impressive bloodlines.

Ace meets with his parole officer and starts to line up potential investors as a public face for his next big venture. Meanwhile, Renzo stumbles into a risky proposition by making claim on a horse trained by Escalante; Jerry takes a beating at a high-stakes poker table; and Walter finds a seasoned jockey for his prized thoroughbred, much to Rosie's dismay.

Ace meets with Claire about a charitable endeavor for prisoners, and discusses his new venture with an old partner. Meanwhile, Jerry’s gambling nemesis lures him into a dangerous game that may require an intervention by his racetrack buddies; and Walter turns to Rosie to be his new jockey.

Ace takes the reins when Escalante surprises Gus with his decision to race Pint of Plain with an inexperienced jockey in the horse's debut. Meanwhile, Marcus delves into the meaning of his friendship with Jerry; and Claire accompanies Ace to the track after accepting his very generous donation.