On the southern coast of Devon, the crew at Salcombe lifeboat station reacts to a distress signal from a fisherman who has become trapped underwater in his own fishing equipment, and a severe fire on a boat located fifteen miles out in the channel.

A lifeboat team in Courtown, Ireland, faces the task of keeping a teenage girl, suspected of having spinal injuries, immobile and buoyant for forty minutes.

The crew stationed at the Tower in Central London, the most active of the RNLI's 238 locations, monitoring the River Thames is called to a man reported in the water eight miles downstream; they discover a river bus already on the site.

In Brighton, the crew is called for what they believe to be a standard operation to tow a powerless yacht back to the harbor; a spring storm and towering waves force the crew to battle not only for the yacht's safety but also for their own survival.

In Torbay, Devon, the seas frequently teem with sailing crafts of various shapes and sizes; when two boats collide, the Torbay lifeboat crew is dispatched to offer emergency medical aid for potentially serious injuries.

At Anstruther station in Scotland, George takes command for his inaugural response to a critical medical evacuation; A woman has fallen in one of the most treacherous areas of the station's jurisdiction, where hikers must navigate steep cliffs.