Sam and Dean follow the coordinates left in their father's journal and land in the middle of the Colorado woods where they investigate the disappearance of several campers.

In a small town in Wisconsin, Sam and Dean investigate a series of mysterious drownings officially explained as suicides.

On TransNational flight 2485, a man possessed by the spirit of the Phantom Traveler causes the plane to crash, leaving only five survivors. Sam and Dean must exorcise the angry spirit before it attacks the survivors.

In suburban Nebraska, several partying high school teens jokingly dare their friend Charlie to look into a mirror and repeat 'Bloody Mary' three times, not knowing that this will unleash a series of mysterious murders.

Sam and Dean help Sam's old college buddy after he is accused of a murder he swears he didn't commit. The brothers discover a shape-shifter is adopting the likenesses of others and murdering people.