Chelsey has battled weight her whole life, avoiding Dr. Now's program since age 9; now 25, she's ready to leave her unhealthy home and see the world; but first, she must prove she's ready to commit to the steps that will transform her future.

As identical twins, Destinee and Dynastiee, have always done everything together…including gaining weight. At over a collective 1200 lbs, they both are determined to get healthy and lose the weight with Dr. Now's help.

Destinee and Dynastiee continue their weight loss journey, but, after only one of them qualifies for surgery, the thought of moving ahead without the other is too much. They decide to do it together or not at all, knowing if one fails they both fail.

After losing her son and her marriage, Trista turned to food, reaching over 600 lbs.; ready to heal, she seeks Dr. Now's help.