17-yr-old Chris Daigle vanishes shortly after leaving Hightower High School for the day in Missouri City, TX. Family members and law officials spend years dissecting the weeks and months leading up to the day the baseball all star disappears.

Teenagers Cheryl Miller and Pam Jackson vanish while spending the first day of summer break in the small town of Vermillion, S.D.; the teenagers' families never give up hope of finding them, then, one day, the truth is revealed.

On the small island of Oahu, Hawaii, Charlotte Moriarty and her infant son take a five-minute stroll to the market but never come home; it will take more than 30 years to find out what happened to the missing woman and her baby.

When Lynda McClelland goes missing from her home in Forest Hills, Pa., she leaves behind three beloved grandchildren and a grief-stricken daughter; an agonizing search for McClelland uncovers answers that lie painfully close to home.

Thirty-two-year-old Michele Whitaker is leading a troubled life when she disappears without a trace; her family and police investigate every possible lead for six years, then, a telephone call gives them the answers they're looking for.

After Dena Raley-McCluskey vanishes from Modesto, Calif., investigators focus on her ex-boyfriend with whom she had a tumultuous relationship; the police are stumped for years until an unexpected break in the case uncovers the shocking truth.