Saige Ryan Campbell

The eldest daughter of a family involved in a car crash must make a difficult decision; Teddy asks Cristina to help with an O.R. patient; Lexie works with Mark's new girlfriend during a surgery.

A casting change puts 'Medellin' back on the table for Vince. Ari and producer Nick Rubenstein must broker the deal between Amanda and the studio by day's end, but because it's Yom Kippur they can't use the most important tools of their trade (cell phones) until after sundown. Eric suspects that Vince and Amanda's relationship is sabotaging the deal. At the races, Drama saves an injured horse from the glue factory.

Cuddy gives some of her day-to-day responsibilities to Cameron; the team takes on the case of a teacher who collapsed after spitting up blood during a class.