An emotional thrill ride through the day-to-day chaos of the city's newest trauma centre and into the lives of the courageous doctors, nurses and staff who hold it all together.
EPISODE 1
Derailed
The staff of Gaffney Chicago Medical Center's new ER are given a baptism of fire when the department's opening is interrupted by a train crash.
EPISODE 2
iNO
Dr Choi treats a teenage mother who abandoned her newborn baby in an alley. The nurses surprise Dr Manning with a baby shower.
EPISODE 3
Fallback
Dr Rhodes takes on a tricky case with a familiar patient, and Dr Halstead must decide whether to gamble on a young musician's hearing by performing surgery.
EPISODE 4
Mistaken
A mass shooting at a cinema inundates the hospital with gunshot victims, including the shooter. Dr Rhodes faces a crisis of conscience.
EPISODE 5
Malignant
Rhodes and Zanetti race to save a member of Firehouse 51, April's brother struggles during his first day at the hospital, and a woman saved from a burning building leads to a bigger mystery.
EPISODE 6
Bound
Dr Rhodes tends to two injured aeroplane stowaways, but their treatment becomes complicated when the Department of Homeland Security arrives.
Oliver Platt
S. Epatha Merkerson
Nick Gehlfuss
Marlyne Barrett
Yaya DaCosta
Steven Weber
Torrey DeVitto
Colin Donnell
Rachel DiPillo
Jessy Schram
Brian Tee