After witnessing the mysterious death of his brother when he was a child, Ryuhei now leads a normal high school life. But when a strange creature named Toris bites him, he has a strange dream, one that will change his life forever.

One of Ryuhei's classmates is suffering from an abusive father and stifling home life. She turns to a mysterious drug to escape from her problems, but the drug has a connection to the strange world that Ryuhei is investigating.

A young girl named Tomomi is bullied and ignored at school. She dreams of being popular and famous, but when the Somnium Drug gives her the chance to make her dreams come true, things take an unexpected turn...

Aruto seems like a normal boy and a valuable member of the team. But at home, he's dealing with a lot of problems, including a suicide and depressed mother...

When a young boy loses his sister to a brutal murder, the Somnium Drops give him a chance to get the revenge he can't get from the justice system.

The team finds an unexpected break in their search when a girl comes to them for help. But she's more than she seems, and the Church will do anything to get her back.