Lauren Potter
In 2009, Potter received a call from the Down Syndrome Association's in-house talent agency, Hearts and Hands, about a potential role on "Glee." She auditioned and landed the part of Becky Jackson, a 16-year-old sophomore at McKinley High School who, despite her mental handicaps, manages to impress its gruff coach, Sue Sylvester (Jane Lynch) and earn a spot in the elite cheerleading squad. Landing the role on the top-rated series was not only ironic for Potter - she actually tried out for cheerleading at her high school and did not make the cut - but it was also a life-changer. While Potter's shy and sweet-natured character started off as a pawn in one of Sylvester's many ill-fated schemes to destroy the glee club, she managed to break down Sylvester's steely exterior to reveal a softer side. Potter's storyline became more involved as she became Sylvester's unlikely underling whose job it was to spy on and report the glee club's every move to her scheming coach. By the show's second season, Potter's character was undeniably a crowd favorite. The actress used her popularity to bring attention to an issue that was near and dear to her heart. She became active in causes that sought to end the taunting and bullying of children with special needs.