When the team treats a patient who has to decide whether to undergo a dangerous surgery that could change his life, he asks Shaun what he would do.
Under the influence of red kryptonite, Clark is following a life of crime in Metropolis while his friends and parents desperately try to find him. Lex is forced to confront his personal demons on a desert island, while Lionel holds a funeral for his presumed-dead son. And Jonathan Kent must pay a high price for the power necessary to bring his son back home.
Joe and Marybeth try to reconnect as Joe is shut out of the murder investigation. Nate and Cricket seek answers to past secrets while on the run.
Henry asks Violet out; those searching for Gold break into Emma's house, where they find a glimpse of Emma's end game; Merida tackles her mission.
During an investigation into the strange suicide of a scientist specialising in biochemical engineering, FBI special agents Mulder and Scully contend with memories of their missing son William.