`Duck Quacks Don't Echo' experiments with the fun side of science. Celebrities put weird, unusual and over-the-top hypotheses to the test in a breezy, lighthearted and often hilarious manner. The "mad scientists" challenge one another in each hour-long episode with three different theories and then go about trying to prove their validity by any means necessary. Scientific professionals explain the why and the how behind some of the surprising results, and once each panellist has defended his honour by carrying out an experiment, a winner is picked. Whose theory is the most impressive, outrageous or interesting?