Puss must protect the magically veiled city of San Lorenzo after he exposes it to the world by accidentally reversing an ancient protective spell.

Puss accidentally gives the orphans a magic sugar that proves to be dangerous, and the only cure is guarded by a powerful sphinx.

When Toby's ninja brothers try to get him to steal San Lorenzo's treasure, he must decide between them and his friendship with Puss.

The Duchess, who wants to rule the world by harnessing the power of sorcerers, captures Artephius and it is up to Puss to rescue him.

Puss is tricked into going on a quest with an old friend, Jack Spratt. What starts out as a mission to save a princess soon turns dangerous.

Puss and Dulcinea embark on an adventure to find the Fountain of Youth to save Puss' old mentor, El Guante Blanco.