Mike Wolfe and Frank Fritz are Midwestern pickers that travel across America in search of rare artefacts and national treasures that they can buy from the collectors they visit and then sell in their antiques shops or, in some cases, put in their personal collections. They usually have to dig through boxes or piles filled with items that have accumulated over the years, which are often located in such places as barns or spare rooms in the owners' homes. While the guys are willing to buy pretty much anything old, their particular interests include items having to do with the auto industry and classic toys.