Miami detective Sonny Crockett reluctantly teams with New York cop Rico Tubbs when both of them end up pursuing a drug dealer who killed their partners.

Crockett and Tubbs are sceptical of rumours the undercover FBI agent (Ed O'Neill) has betrayed their operation.

Crockett and Tubbs must enlist an unreliable petty thief (Charlie Barnett) to help bust a Jamaican drug operation.

Tubbs works to save Crockett and family from falling victim to an Argentine assassin hired by drug boss Calderone.

The vice detectives track Calderone to the Bahamas, where Tubbs becomes involved with the drug lord's daughter.

Crockett attempts to help an old flame free herself from a racketeer, then is framed for taking bribes.